Most modern pistol cans are user serviceable and not fully sealed. Those cans can be cleaned. I haven't noticed any lead build up as a result from running FMJ's. The majority of build up in cans I have examined has been carbon, not lead. With the exception being 22lr cans.
I have one sealed can I use for PCC/SMG guns, but it is also rifle rated, so a few rounds of full power 308 tends to shake loose any build up.
I played around with plated projectiles for a few years, and I could never get good accuracy or consistency, I'd always end up with at least one bullet out of 50/100 tumbling. I primary shoot uspsa, so the accuracy mattered to me. If you aren't using mixed brass, and very diligent with your reloading practices you may have better luck than I did. I typically load 10-20k a year and it's just not worth it.
I wouldn't personally trust plated projectiles that I loaded to not tumble or cause issues in my can. As always I'm talking about my personal experience and YMMV.